Custom Model Generation

TransViragen is a premier provider of services for the creation of genetically engineered mice and rats.  We use a broad range of technologies and offer the most complete selection of custom model generation services in the marketplace.  With a dedicated commitment to customer satisfaction, TransViragen provides clients with innovative and flexible service offerings to meet their specific requirements, as well as nimbleness to quickly adapt to their changing priorities.  And our comprehensive full-service guarantees are unsurpassed in the industry.  Our clients have come to value the TransViragen advantage for reliable, timely and cost-effective solutions to their research model needs.

Contact us today for a free consultation.  Our expert scientists will take the time to discuss your model requirements and provide you with guidance on specific design options.

The wide variety of model types available from TransViragen include:

Mouse Models

Constitutive Knockout – mouse model with complete inactivation of the targeted gene in every tissue

Conditional Knockout – mouse model in which inactivation of the targeted gene can be controlled in a tissue-specific and/or temporal manner

Knock-in – mouse model with targeted insertion of a genetic element, such as a human gene, reporter gene, point mutation or regulatory element, into an endogenous locus.

Conditional Knock-in -  mouse model in which insertion of a genetic element into an endogenous locus can be controlled in a tissue-specific and/or temporal manner

IKMC Models – mouse models generated using materials from the International Knockout Mouse Consortium (KOMP / EUCOMM / NorCOMM)

Transgenic – mouse model with random insertion of a transgene construct

BAC Transgenic – mouse model with random insertion of a BAC transgene construct

Rat Models

Constitutive Knockout – rat model with complete inactivation of the targeted gene in every tissue

Conditional Knockout – rat model in which inactivation of the targeted gene can be controlled in a tissue-specific and/or temporal manner

Knock-in – rat model with targeted insertion of a genetic element, such as a human gene, reporter gene, point mutation or regulatory element, into an endogenous locus.

Conditional Knock-in – rat model in which insertion of a genetic element into an endogenous locus can be controlled in a tissue-specific and/or temporal manner

Transgenic – rat model with random insertion of a transgene construct

BAC Transgenic – rat model with random insertion of a BAC transgene construct